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10671885 Cancer diagnostic method and system  
A method and system for classifying tissue suspected of being abnormal as being malignant or benign. The method includes generating a set of selection features, performing statistical applications...
10670603 Diagnosis and treatment of cancer expressing ILT3 or ILT3 ligand  
The present invention relates to methods of using the expression of ILTL3 ligand or ILT3 on certain types of cancer cells as a diagnostic tool. Methods are provided for treating ILT3-ligand...
10669589 Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments  
Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will...
10669588 Methods for sub-typing and treating cancer  
This invention relates to a novel approach for the identification and stratification of subtypes of cancer, particularly pancreatic ductal adenocarcinoma (PDAC). The invention furthermore relates...
10669584 Cancer antigen-specific T-cell receptor gene, peptide encoded by the gene, and use of them  
Disclosed are: a nucleotide sequence and an amino acid sequence for CDR3 region of T-cell receptor (TCR) gene of WT1-specific cytotoxic T-cell (CTL) for WT1 protein; a method for the detection or...
10669536 Diagnosis of prostate cancer  
The invention provides methods for isolating RNA from whole urine and urine fractions for the diagnosis of prostate cancer and/or benign prostate hyperplasia. An exemplary method for diagnosing...
10669349 Compositions and methods for treatment of cancer  
Compositions, e.g., compositions comprising cellular therapeutics and/or protein therapeutics, and methods of using such compositions for treating cancer are described.
10669326 Peptides, combination of peptides as targets and for use in immunotherapy against gallbladder cancer and cholangiocarcinoma and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10669325 Uterine cancer treatments  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10669310 Peptide for cancer treatment and pharmaceutical composition containing same  
The present invention provides peptides containing a structure in which a portion of the dominant negative peptide of BIG3 which inhibits the interaction between BIG3 and PHB2 is substituted with...
10669234 Cyanopyrrolidines as dub inhibitors for the treatment of cancer  
The present invention relates to novel compounds and method for the manufacture of inhibitors of deubiquitylating enzymes (DUBs). In particular, the invention relates to the inhibition of...
10668174 Organ protection in PSMA-targeted radionuclide therapy of prostate cancer  
A method of reducing radiation exposure of a non-cancerous tissue of a patient diagnosed with a cancer includes administering to the patient an agent capable of competing for binding sites on a...
10668166 Antibody-drug-conjugates comprising novel anthracycline-derivatives for cancer treatment  
The present invention relates to novel anthracycline derivatives comprising two oxazolidine cycles and the preparation of said anthracycline derivatives. Furthermore, antibody-drug conjugates...
10668152 Use of anti-PD-1 antibody in combination with anti-CD27 antibody in cancer treatment  
This disclosure provides methods for treating cancer in a subject comprising administering to the subject an anti-PD-1 antibody and an anti-CD27 antibody. In some embodiments, the cancer is...
10668151 Nanoparticle complexes of albumin, paclitaxel, and panitumumab for treatment of cancer  
This invention relates to antibody-albumin nanoparticle complexes comprising albumin, an antibody with binding specificity for a cancer antigen (e.g. panitumumab), and paclitaxel, wherein the...
10668138 Peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10668130 Formulation for targeting cancer in humans and canines using chlorotoxin  
The present invention provides formulation/composition comprising phytonutrients with natural chlorotoxins for targeting cancer, infection, inflammation and pain without any side effects and a...
10668125 Peptide having highly-shifted accumulation to pancreatic cancer cells and tissues, and use of said peptide  
Disclosed is a peptide of the following (a) or (b): (a) a peptide containing an amino acid sequence including a sequence set forth in any one of SEQ ID NOS: 1, 2, 3, and 4; and (b) a peptide...
10668113 Formulation for targeting cancer in humans and canines using venom  
The present invention provides formulation/composition comprising phytonutrients with natural chlorotoxins for targeting cancer, infection, inflammation and pain without any side effects and a...
10668112 Formulation for targeting cancer in humans and canines  
The present invention provides formulation/composition comprising phytonutrients with natural chlorotoxins for targeting cancer, infection, inflammation and pain without any side effects and a...
10668093 Method for prolonging the over survival of a cancer patient  
The present invention relates to a method for treating a cancer with the combination of a topoisomerase II inhibitor (TOP2 inhibitor) and a histone deacetylation inhibitor (HDACi), provides...
10668078 Methods and compositions for treating mesothelioma and small lung cancer that express midkine  
Embodiments provided herein relate to methods and compositions for treating mesothelioma and/or a small cell lung cancer that express midkine.
10668068 Treating cancer with drug combinations  
Embodiments of the invention find application in the field of cancer therapy. Receptor protein kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins,...
10668063 Method of treating cancer associated with a RAS mutation  
Disclosed herein are methods of treating a cancer characterized by expressing a mutant form of a RAS protein. Some embodiments relate to treatment of cancer by administering Plinabulin to a...
10668055 Cancer treatment using combinations of ERK and RAF inhibitors  
The present invention provides, inter alia, methods of treating or ameliorating the effects of a cancer in a subject. The methods include administering to the subject an effective amount of (i) a...
10668028 Methods and use of inducing apoptosis in cancer cells  
The present disclosure relates to a method of inducing apoptosis in a cancer cell by delivery of exogenous Coenzyme Q1O or its metabolites thereof in a pharmaceutically acceptable carrier to...
10667749 Device, method and system for implementing a physical area network for cancer immunotherapy  
A physical area network described herein enables significantly improved health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and...
10667718 Quantitative prostate cancer imaging with magnetic resonance fingerprinting (MRF)  
Example embodiments associated with characterizing a sample using NMR fingerprinting are described. One example NMR apparatus includes an NMR logic that repetitively and variably samples a (k, t,...
10663470 Immunoassay of S-adenosylmethionine in personalized medicine and health or cancer evaluation  
The invention provides a method of detecting the presence or absence of a disease in a patient wherein said disease is accompanied by deficient levels of S-adenosylmethionine comprising:...
10663469 Method for using information on complex biomarker group to diagnose lung cancer in a subject and diagnostic kit and computing system using the same  
A method for diagnosing lung cancer in a subject by using a complex biomarker group is provided. The method includes steps of: (a) a computing system (1) acquiring a model M by using expression...
10663465 Disruption of EGFR-SAR1 interaction for cancer treatment  
The present invention relates to the discovery that delivery of EGFR to cell surface requires EGFR-SAR1A binding. Thus, the invention provides a method for identifying inhibitors of EGFR-SAR1A...
10663464 CEACAM1 based point-of-care cancer diagnostic  
The present technology regards the utilization of CEACAM1 as a biomarker for cancer. In particular the present invention regards the detection and measurement of soluble CEACAM1 levels for the...
10662478 Serine proteases as biomarkers for ovarian cancer  
The described invention provides methods for detecting, diagnosing and treating low-grade ovarian cancer and stage I ovarian cancer by comparing results from serum and ovarian tissue samples with...
10662441 Viral vector targeting cancer stem cells  
[Problem] To provide a novel and effective method for treating cancer, method for preventing cancer, and method for suppressing metastasis by targeting cancer stem cells, the methods being capable...
10662247 Compositions and methods of use for augmented immune response and cancer therapy  
The present invention provides antibody compositions, including, e.g., antibodies, engineered antibodies and antibody fragments that bind to a tumor necrosis factor receptor superfamily member...
10662233 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC and other cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The...
10661095 Photodynamic therapy for use in treating cancer  
Disclosed is the use of copper cysteamine nanoparticles for use in photodynamic cancer therapy. The disclosed methods of treatment utilize microwave radiation as a means for activating the copper...
10660955 Cancer methods  
A method of treating a patient having a cancer in which HER2, HER4, FGFR1, EPHA2 and/or FGFR3 is upregulated and/or in which HER2, HER4, FGFR1, EPHA2 and/or FGFR3 mediated-signaling is...
10660954 Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer  
The novel synergistic combination of immune checkpoint blockade and hematopoietic stem cell transplantation and/or hematopoietic stem cell mobilization yield synergistic effects in disease therapy.
10660931 Herbo-mineral formulation for the treatment of cancer and method of preparation thereof  
Herbo-mineral formulation for the treatment of cancer and method of preparation are disclosed herein. The disclosed formulation includes a combination of herb and mineral components that...
10660912 Combination therapy for cancer  
Disclosed is a combination of gemcitabine-[phenyl-benzoxy-L-alaninyl)]-phosphate (chemical name: 2′-Deoxy-2′,2′-difluoro-D-cytidine-5′-O-[phenyl (benzoxy-L-alaninyl)]phosphate) (NUC-1031) and a...
10660909 Method for treating cancer using chemokine antagonists  
What is described is a method for treating cancer in a patient in need of such treatment through the use of an antagonist to CXCR1 and/or CXCR2 receptors by administering a therapeutically...
10660889 Compounds for treatment of cancer  
The present invention relates to compounds as inhibitor of WNT signal transduction pathway, as well as a composition comprising the same. Further, the present invention relates to the use of the...
10660861 Glutaminase inhibitor discovery and nanoparticle-enhanced delivery for cancer therapy  
Currently available glutaminase inhibitors are generally poorly soluble, metabolically unstable, and/or require high doses, which together reduce their efficacy and therapeutic index. These can be...
10660565 Device, method and system for implementing a physical area network for cancer immunotherapy  
A physical area network described herein enables significantly improved health monitoring and treatment by utilizing internal (in-body) mechanisms and information and external mechanisms and...
10657644 Breast cancer detection  
A hybrid detection model may be used for breast cancer detection. A system can identify a region of interest on a received mammogram. The region of interest may have a particular level of grey at...
10656155 Serum-based biomarkers of pancreatic cancer and uses thereof for disease detection and diagnosis  
Biomarkers of pancreatic cancer are described, as well as methods using these compounds for detecting pancreatic cancer. The methods can be used to diagnose a patient's health state, or change in...
10656154 Methods for detecting an amount of complement factor B protein and carbohydrate antigen 19-9 protein, and methods for diagnosing and treating pancreatic cancer using the same  
The present application relates to a kit for diagnosing pancreatic cancer, a method for providing information for diagnosing pancreatic cancer using the kit, and a method for diagnosing pancreatic...
10655187 Genetic marker for early breast cancer prognosis prediction and diagnosis, and use thereof  
The present invention relates to a gene for predicting or diagnosing the prognosis of early-stage breast cancer and to a use thereof, and more specifically relates to a genetic marker for...
10655186 Point mutations in TRK inhibitor-resistant cancer and methods relating to the same  
Provided herein are methods of treating a subject having a cancer, methods of selecting a treatment for a subject having a cancer, methods of selecting a subject having a cancer for a treatment...

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